Main Speakers & Final Program

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Evangelos Andreakos, PhD Biomedical Research Foundation, Academy of Athens, Athens, Greece @VangelisAndrea1
Megan Tierney Baldridge, MD, PhD, Washington University School of Medicine in St. Louis, USA @baldridge_lab
Steeve Boulant, PhD, University of Florida, Gainesville, USA @BoulantLab
Carolyn B. Coyne, PhD, Duke University School of Medicine, Durham, USA @scienceCC
Jordan Feld, MD, MPH, Toronto General Hospital Research Institute (TGHRI), Toronto, Canada
Paul Hertzog, PhD, Centre for Innate Immunity and Infectious Disease Hudson Institute of Medical Research Clayton VIC Australia @pjhpauljh
Sergei V. Kotenko, Ph.D., M.S., Rutgers New Jersey Medical School, USA
Juan Mendoza, PhD,,Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, USA @DrJuanLMendoza
Charlotte Odendall, PhD, King's College London, UK @COdendall
Co-Chair: Ludmila Prokunina-Olsson, Ph.D., National Cancer Institute, USA @prokuninaolsson
Ram Savan, Ph.D., University of Washington, Seattle, USA
Co-Chair: Ivan Zanoni, PhD, Harvard Medical School, Boston Children's Hospital, USA @Lo_Zanzi

Final Program for IFNL2022- (Hawaii time zone)

Saturday, September 24 
Interferon Lambda: Inflammation and Infection in Experimental Models 
Moderator: Juan Mendoza, University of Chicago, USA 
Session 1startpresenteraffiliationin person/virtualtitle
18.00Mila Prokunina-OlssonNational Cancer Institute, USAin-personOPENING REMARKS
28.05Nabiha YusufUniversity of Alabama at Birmingham, USAvirtual from USINTERFERON LAMBDA SIGNALING RESTRAINS DEVELOPMENT OF EXPERIMENTAL AUTOIMMUNE ENCEPHALITIS
38.18Da’ Kuawn JohnsonUniversity of Maryland School of Medicine, USAvirtual from USAGE-DEPENDENT ROLE OF INTERFERON LAMBDA IN AN INFANT MOUSE MODEL OF BORDETELLA PERTUSSIS INFECTION
48.31Ryan MartinezUniversity of Minnesota, USAvirtual from USTYPE III INTERFERON DRIVES THYMIC B CELL ACTIVATION AND CENTRAL TOLERANCE
58.44Megan BaldridgeWashington University School of Medicine in St. Louis, USAin-personCELLULAR CROSSTALK BY IFN-LAMBDA CONTROLS ENTERIC MURINE NOROVIRUS
69.07Priyanka TalukdarUniversity of Pittsburgh School of Public Health, USAin-personINTERFERON LAMBDAS ARE EXPRESSED IN TUBERCULOSIS GRANULOMAS AND PROMOTE MACROPHAGE ANTIMYCOBACTERIAL ACTIVITY
79.20Charlotte OdendallKing’s College London, UKin-personINTERFERON: TUG OF WAR BETWEEN HOST AND PATHOGEN
89.43Danielle AntosUniversity of Pittsburgh, USAin personINTERFERON LAMBDA ALTERS IMMUNE FUNCTION DURING INFLUENZA, BACTERIA SUPER-INFECTION
99.56Ivan ZanoniHarvard Medical School, Boston Children’s Hospital, USAin-personINTERFERON LAMBDA CONTROLS INTESTINAL INFLAMMATION
10.20 – 10:50 Coffee/poster break
 
Interferon Lambda: COVID-19, Regulation and Tissue Microenvironment  
Moderator: Deanna Santer, University of Manitoba, Canada 
Session 2startpresenteraffiliationin person/virtualtitle
110.50Jordan FeldToronto General Hospital Research Institute, Canadavirtual from CanadaPEGYLATED-IFN-LAMBDA AS A THERAPEUTIC FOR COVID-19
211.13Emily HemannOhio State University, USAin-personINTERFERON-LAMBDA SIGNALING REGULATES DISEASE SEVERITY AND CD8 T CELL IMMUNITY IN A MURINE MODEL OF SARS-COV-2 INFECTION
311.26Henry YangDuke University, USAvirtual from USINNATE IMMUNE SIGNALING IN TROPHOBLAST AND DECIDUA ORGANOIDS DEFINES DIFFERENTIAL ANTIVIRAL DEFENSES AT THE MATERNAL-FETAL INTERFACE
411.38Steeve BoulantUniversity of Florida, USAin-personLOW OXYGEN LEVELS IN THE HUMAN GUT INFLUENCES THE IMMUNE FUNCTIONS OF INTESTINAL EPITHELIAL CELLS
512.01Austin WrightOregon Health and Science University, USAin personCRISPR SCREENS IDENTIFY INTERFERON REGULATORY FACTOR 6 AS A POTENTIAL REGULATOR OF INTERFERON SIGNALING IN THE INTESTINAL EPITHELIUM
612.14Emmanuel ThomasUniversity of Miami School of Medicine, USAin-personINTERFERON INDUCED ISGYLATION IS DIFFERENTIALLY REGULATED AS INDUCED-PLURIPOTENT STEM CELLS DIFFERENTIATE TO EPITHELIAL CELLS
812.27Evangelos AndreakosAcademy of Athens, Greecein-personTYPE III IFNS IN ANTIVIRAL IMMUNITY AND BEYOND
712.50Emily MesevPrinceton University, USAin-personINTRACELLULAR DOMAINS OF TYPE I AND III INTERFERON RECEPTORS ENCODE DIFFERENCES IN JAK-STAT SIGNALING MAGNITUDE
 
Sunday, September 25 
Interferon Lambda: Human Genetic Associations and Molecular Functions   
Moderator: Thomas O’Brien, National Cancer Institute, USA 
Session 3startpresenteraffiliationin person/virtualtitle
18.00Sreedhar ChinnaswamyNational Institute of Biomedical Genomics, Indiavirtual from IndiaLEISHMANIA DONOVANI INFECTION INDUCES IFN-Λ3 IN CELLS, MICE, AND HUMANS
28.13Tsion MinasNational Cancer Institute, USA/Ethiopiavirtual from EthiopiaHUMAN HERPESVIRUS 8 INFECTION IS ASSOCIATED WITH PROSTATE CANCER AMONG IFNL4-ΔG CARRIERS
38.26Michelle FangNational Cancer Institute, USAvirtual from USNO ASSOCIATION OF IFNL4 GENOTYPE WITH OPPORTUNISTIC INFECTIONS AND MALIGNANCIES AMONG MEN WITH HIV-1 INFECTION
48.35Francine BakerNational Cancer Institute, USAvirtual from USEXPLORING THE ASSOCIATION OF IFNL4 VARIANTS WITH THE RISK OF BURKITT LYMPHOMA IN 4000 CHILDREN FROM SUB-SAHARAN AFRICA
58.48Carolyn CoyneDuke University, USAVirtual from USIFNLs IN SOME OTHER PLACENTAL ORGANOIDS 
69.11Megan StaniferUniversity of Florida, USAin-personCELL TYPE SPECIFIC RESPONSE TO VIRAL INFECTION IN THE HUMAN GASTROINTESTINAL TRACT
79.24Mila Prokunina-OlssonNational Cancer Institute, USAin-personNEW INSIGHTS INTO MOLECULAR FUNCTIONS OF IFNL4
89.47Ram SavanUniversity of Washington, USAin-personTHE COMMON IL-10 RECEPTOR CHAIN FINDS SPACE FOR PRIVATE INTERACTIONS AWAY FROM THE CROWD
10.10 – 10:50 Coffee/poster break
 
Interferon Lambda: Crosstalk, Structure and Therapeutics  
Moderator: Rune Hartmann, University of Aarhus, Denmark 
 
Session 4startpresenteraffiliationin person/virtualtitle
110.50Paul HertzogHudson Institute, Australiain-personCROSSTALK BETWEEN TYPE I AND TYPE III INTERFERONS
211.13Jorna SojatiUniversity of Pittsburgh School of Medicine, USAin personTYPE I AND III INTERFERON DRIVE NON-REDUNDANT AND AIRWAY SITE-SPECIFIC ANTIVIRAL IMMUNE RESPONSES IN HUMAN METAPNEUMOVIRUS INFECTION
311.26Bibiana CostaCenter for Experimental and Clinical Infection Research, Germanyin-personHCMV EXPLOITS STING SIGNALING AND COUNTERACTS ISG AND IFN-Β, BUT NOT IFN-Λ1 INDUCTION TO FACILITATE VIRAL GENE EXPRESSION IN MONOCYTE-DERIVED DENDRITIC CELLS
411.39Noemie AlphonseKing’s College London, UKin personTYPE I AND III INTERFERONS AT THE INTERFACE BETWEEN BACTERIAL PATHOGENS AND THEIR HOST
512.02Deanna Santer University of Manitoba, Canadain personDYSREGULATED INTERFERON-LAMBDA RECEPTOR LEVELS IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE
612.14Juan MendozaUniversity of Chicago, USAin-personTHE ROLE OF JAK-RECEPTOR INTERACTIONS IN TUNING THE ACTIVITY OF TYPE III INTERFERONS
712.37William GrubbeUniversity of Chicago, USAin-personTOWARDS STRUCTURAL AND FUNCTIONAL STUDIES OF IFN-LAMBDA1-4 USING PROTEIN ENGINEERING AND MOLECULAR DYNAMICS SIMULATIONS
812.50Sergei KotenkoRutgers University, USAin-personDEVELOPMENT OF IFN-BASED THERAPEUTICS
913.13Ivan ZanoniHarvard Medical School, Boston Children’s Hospital, USAin-personCLOSING REMARKS